gut.bmj

Letter to the editor regarding: Lai, Jimmy Che-To, et al "Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated ...

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Gut

Norepinephrine promotes tumour cell aggressiveness and NK cell ferroptosis via ADRB2 in intrahepatic cholangiocarcinoma with perineural invasion

Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, ...
Gut

Loss of sinusoidal endothelial identity: RAP1A at the crossroads of capillarisation and liver fibrosis

Liver fibrosis represents a serious worldwide health issue with a prevalence of around 5% in general populations.1 The most ...
Gut

Tryptophan depletion generates hyper-reactive portal neutrophils in alcoholic liver disease

Background Neutrophils guarantee a prompt and robust host response to pathogens. Yet, overshooting neutrophil activation ...
gut.bmj

Cyclooxygenase (COX) 1 and 2 in normal, inflamed, and ulcerated human gastric mucosa

a Division of Gastroenterology, University Hospital, Nottingham, UK, b Division of Pathology, University Hospital, Nottingham, UK Professor C J Hawkey, Division of Gastroenterology, University ...
gut.bmj

A prospective national study of acute fatty liver of pregnancy in the UK

Guys and St Thomas’ Hospitals NHS Foundation Trust, London, UK Dr M Knight, National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Oxford OX3 7LF, UK; marian.knight{at}npeu.ox.ac ...
gut.bmj

Appearances can be deceiving: an ulcerated oesophageal lesion

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Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks

3 College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA Objective Despite widespread use of antibiotics for the treatment of life-threatening infections and for research on ...
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Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis

Gene Expression Unit, Department of Molecular Cell Biology, Katholieke Universiteit Leuven, Leuven, Belgium Background and aims: Infliximab is an effective treatment for ulcerative colitis with over ...
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Global incidence of oesophageal cancer by histological subtype in 2012

Correspondence to Dr Melina Arnold, Section of Cancer Surveillance, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon 69008, France; arnoldm{at}fellows.iarc.fr Objective The ...
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Oleic acid promotes lung injury in hypertriglyceridaemia-associated acute pancreatitis via the PIEZO1/NR4A1/CPT1A axis impairing endothelial fatty acid oxidation

Background Hypertriglyceridaemia-induced acute pancreatitis (HTG-AP) is frequently complicated by acute lung injury (ALI), which worsens prognosis. Oleic acid (OA), a major circulating free fatty acid ...
gut.bmj

E-cadherin loss in Cd44-positive gastric cells initiates diffuse gastric cancer in a murine model

Background CDH1 is commonly mutated in sporadic diffuse gastric cancer (DGC) and germline CDH1 mutations underlie most cases of the cancer syndrome hereditary DGC. Objective We aimed to develop mouse ...